Amine oxidation under challenging conditions: Implementation of a flow-chemistry procedure for 3,4-dinitrofurazan synthesis

Abstract. 3,4-Dinitrofurazan (DNF) is both a liquid energetic material with unique properties and an excellent starting material for synthesis. Its batch synthesis is hazardous and time consuming. Therefore, we recently developed a novel microreactor based flow-chemistry procedure for the oxidation of DAF with commercially available hydrogen peroxide (70%) and concentrated sulfuric acid at elevated temperatures up to 60 °C. A yield of 32% DNF was received in preliminary experiments exploring suitable parameters for future studies. The herein presented process significantly increases safety in providing DNF on a laboratory scale and does not require the use of elemental fluorine or unusual reagents.